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Misoprostol In this paper we demonstrate
2022-01-14

In this paper, we demonstrate a Misoprostol based TLC-SERS sensing technique combined with machine learning analysis to quantitatively detect seafood allergen in real spoiled tuna samples. We fabricate a diatomaceous earth TLC plate as a separable SERS-active substrate to detect histamine in artifi
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br An approach for the key challenges facing forensic
2022-01-14

An approach for the key challenges facing forensic science One of the key challenges for forensic science is to avoid being side-tracked by one of the louder narratives in the media that the big problem forensic science faces is ‘junk science’ and ‘rogue scientists’. These are clearly important i
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br Conclusion The addition of cellulose to natural substrate
2022-01-14

Conclusion The addition of Pexmetinib to natural substrate increases the number of H-bonds which indicates an increase in the stability of the docking systems. The investigated compounds are more stable than natural substrate in docking systems, where the natural substrate has two H-bonds while t
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Curcumin is a major yellow pigment in turmeric ground rhizom
2022-01-14

Curcumin is a major yellow pigment in turmeric ground rhizome of Curcuma longa Linn, which is used widely as a spice and coloring agent in several foods such as curry, mustard and potato chips as well as cosmetics and drugs (Okada et al., 2001, Joe et al., 2004). Curcumin represents a class of anti-
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Here we studied the effects of BZ flurazepam FZ at
2022-01-14

Here we studied the effects of BZ flurazepam (FZ) at high doses in acute and chronic settings of tolerance and dependence in GluR-A−/− mice (Zamanillo et al., 1999). We used measurements in which the phenomenon of “learning while intoxicated” should play only a minor role in order to find out the si
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leonurine In teleosts GR is expressed
2022-01-14

In teleosts, GR is expressed in almost every cell and regulates genes controlling development, metabolism, and immune response [17,18]. Several teleosts contain two GR genes, GR1 and GR2 [8]. Other groups have found only one GR in some species thus far, such as the Japanese flounder, brown trout, an
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Fmoc-Trp-OH Overnight mg dexamethasone suppression testing
2022-01-14

Overnight 1-mg dexamethasone suppression testing (DST) of the BclI polymorphism carriers found them to have lower cortisol levels, suggesting an increased sensitivity to GCs with respect to the transrepression effect of cortisol on the POMC gene of the corticotroph pituitary cells [28]. The exact me
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The relationship between estrogen and
2022-01-14

The relationship between estrogen and the Hedgehog pathway as well as the associated mechanism have already been investigated in many tissues, especially in breast cancer (Chang et al., 2012, Katayama et al., 2006, Ramaswamy et al., 2012). Hitherto, even though we have proved that HH-Gli pathway pro
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Of the cases identified herein three
2022-01-13

Of the 52 cases identified herein, three known and 11 novel FGFR fusion partners were identified. Notably, an oligomerization domain, including coiled-coil dimerization domains similar to that seen in echinoderm microtubule associated protein like 4 gene (EML4), which is the most common ALK partner
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In spite of decades of research the mechanisms of SV
2022-01-13

In spite of decades of research the mechanisms of SV endocytosis and recycling remain controversial. Accumulating evidence suggests that SV endocytosis occurs by more than one mechanism (e.g. clathrin-independent endocytosis, clathrin-mediated endocytosis, bulk endocytosis; reviewed in (Dittman and
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In comparison to the standard HPLC assay to detect LPV
2022-01-13

In comparison to the standard HPLC assay to detect LPV above or below 1,000 ng mL-1, the accuracy of the PIs-IC strip was 97.8 %, the sensitivity was 100% and the specificity was 97.1 %. This suggests that the PIs-IC strip test has the potential accurately to semi-quantify PI concentrations in plasm
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Our investigation also showed NAC increased the level of
2022-01-13

Our investigation also showed NAC increased the level of DAF and might protect HUVECs from complement activation. NAC, an antioxidant/mucous modifier, has displayed benefits in chronic obstructive pulmonary disease. Martinez de Lizarrondo et al [38] provided evidence that the molecular target underl
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br GPR GPR has been described as
2022-01-13

GPR55 GPR55 has been described as a type 3 cannabinoid receptor due to its ability to detect endocannabinoids and may play a role in the endocannabinoid lipid sensing system [28]. GPR55 is activated by both cannabinoid endogenous agoinsts (endocannabinoids) and non-cannabinoids fatty acids namely
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br Next we explored the SAR around the aryl ring
2022-01-13

Next, we explored the SAR around the aryl ring attached to the pyrrole nitrogen in the presence of the 3-CF and the 2,6-difluorophenylpropionic Adenosine Kinase Inhibitor hydrate sidechain (). The EC value of the unsubstituted phenyl was about 100 nM. The 4-methyl was 2-fold more potent, however e
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br Materials and methods br Results and discussion br Conclu
2022-01-13

Materials and methods Results and discussion Conclusions In summary, the Au@SiO2 based lateral flow sandwich immunoassay for fast detection of EBN-specific glycoprotein has been firstly established by using nanocomposites as signaling-labels and synthesized EBN-specific Rink Amide Resin rec
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