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It must be noted that
2019-06-01

It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop
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br Bile acids as therapeutic
2019-06-01

Bile acids as therapeutic agents Conclusion Bile acids are important physiological agents for nutrient exportin and integrators of glucose, lipid, and energy metabolism control. Bile acid synthesis is tightly regulated to maintain metabolic homeostasis and prevent accumulation of highly toxic
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Education is part of the foundation for
2019-06-01

Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres
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br Detection methods in implantable monitoring
2019-05-31

Detection methods in implantable monitoring device State-of-the-art, implantable, dual-chamber cardiac devices provide useful diagnostic information, including the numbers and duration of automatic mode switch (AMS) episodes upon detection of AT/AF. However, to collect accurate diagnostic informa
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The prevalence of drug induced type
2019-05-31

The prevalence of drug-induced type 1 Brugada pattern among patients with clinical AVNRT was found to be 27.1% by our group [17]. This high prevalence has important implications in terms of the epidemiology of BrS. The prevalence of paroxysmal supraventricular tachycardia (PSVT) (AVNRT and AVRT) in
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br A gest o hospitalar nas unidades mantidas Talvez seja
2019-05-31

A gestão hospitalar nas unidades mantidas Talvez seja o produto de mais expressividade que as oss divulgam. A forma como se gerencia o hospital é nebivolol hcl garantia de colheita dos resultados, seu game over junto à sociedade e junto a sua contratante, a Secretaria de Saúde. É a procura por le
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Evidence of the efficacy of topiramate
2019-05-31

Evidence of the efficacy of topiramate in PTC has been reported in the literature [41,42]. The largest study, an open-label trial by Celebisoy and colleagues [41], demonstrated the non-inferiority of topiramate to acetazolamide in the management of idiopathic intracranial GSK-3 Inhibitor IX in a po
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The indications for epicardial mapping are institutionally v
2019-05-31

The indications for epicardial mapping are institutionally variable but typically performed after a failed endocardial approach or if the etiology of cardiomyopathy suggests a high likelihood of epicardial scar (Fig. 9). Studies of patients with NICM that underwent combined epicardial–endocardial ap
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Prior case reports have described hematological remission in
2019-05-30

Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic propyl on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we report
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br As the global burden of disease shifts
2019-05-30

As the global burden of disease shifts from infectious diseases to non-communicable diseases (NCDs), cancer has increasingly become a major contributor to morbidity and mortality in low-income and middle-income countries (LMICs). Major reasons for these Rupatadine Fumarate Supplier shifts include
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South Africa was the first African country
2019-05-30

South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age
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br Conflicts of interest br Funding This study was supported
2019-05-30

Conflicts of interest Funding This study was supported by grants from the Ministry of Science and Technology, Taiwan (MOST-103-2314-B-002-090). Introduction Ancient schwannoma is an uncommon variant of schwannoma, which arises from the nerve sheath Schwann cells, with a typically long cour
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br Introduction Despite the widespread use of bone targeted
2019-05-30

Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested
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br Conclusion br Conflict of interest
2019-05-30

Conclusion Conflict of interest This work was supported by Medtronic Japan. MN received honoraria from Medtronic Japan, St. Jude Medical Japan and Boston Scientific Japan. YE and TI received honoraria from Medtronic Japan. HS received honoraria from Japan Lifeline. YA, TT, and KK are employees
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The outcome of sinus node modification
2019-05-30

The outcome of sinus node modification with radiofrequency ablation has been reported, but it involves a high invasive risk associated with the ablation. Thus, careful confirmation of the earliest activation site and ablation of that site is important [2,3]. The clinical use of the 3D-mapping system
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