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br Results br Discussion In
2018-11-14

Results Discussion In this study, we identified the existence of non-neuronal ACS in developing prostate epithelium. Activation of ACS promoted the proliferation of epithelial progenitor androgen receptor and inhibited their differentiation to luminal cells. On the contrary, blockade of CHRM3
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The same proof of concept study however revealed that
2018-11-14

The same proof-of-concept study however, revealed that the retrospective application of standardized case criteria will result in a certain amount of missing data and indeterminate results with regard to the case definitions. This was the case whenever critical data that would be required for the ca
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br Authors Contributions br Conflict of Interest
2018-11-14

Authors\' Contributions Conflict of Interest Jeri Kim, MD, acknowledges receipt of nonfinancial support from Merck, which provided 5-mg tablets of finasteride and matching placebos for the study. For the 3years preceding submission, she has no other conflict of interest to report. Ian Thompson
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This study is important because our ability to
2018-11-14

This study is important because our ability to identify enough SNPs for a risk profile for clinical implementation is dependent on combining multiple heterogeneous cohorts. The aim was to show that multi-center radiotherapy cohorts could be harmonized and analyzed to identify risk SNPs by increasing
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Fourth our findings could impact the most widely used
2018-11-14

Fourth, our findings could impact the most widely used pharmacokinetic models of maturation as commonly recommended by regulatory authorities (European Medicines Agency, 2007). Several methods are used to examine the effect of maturation on pharmacokinetic parameters, with the two most common being
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Regarding the anti viral response occurring during ZIKV
2018-11-14

Regarding the anti-viral response occurring during ZIKV infections, few reports using different cell types led to different observations. ZIKV AS (H/PF/2013) has been shown to induce an innate antiviral response in primary human skin fibroblasts characterized by the upregulation of TLR3, DDX58 (RIG-
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br Materials and Methods br Paclitaxel Concentration Determi
2018-11-14

Materials and Methods Paclitaxel Concentration Determination in Cell Pellets and Supernatants Calu-6 cells were treated with 100nM TVB-3166 for 24h or 50nM TVB-3664 for 48h. Paclitaxel was added to the cell culture media to a final concentration of 6nM. After the 2h of incubation with paclitax
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br propose that the absence of violet light VL near
2018-11-14

propose that the absence of “violet” light (VL, near ultraviolet (UV), below 400nm) in our industrialized world is a major contributing factor for the recent epidemic increase in myopia. They conclude from their study that artificial lighting should be revised to include a UV component, as in sunl
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br Sub confluent cultures of HCT cells
2018-11-14

Sub-confluent cultures of HCT116 cells were transiently transfected with phCL-EGFP yielding expression of full-length cathepsin L, which was co-localized with endogenous cathepsin L and also reached the nuclei (see Fig. 7D′ in [1]). In addition, MTT assays were performed with non-transfected, pEGF
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Kinematic data were low pass filtered Hz cutoff
2018-11-14

Kinematic data were low-pass filtered (15Hz cutoff; Matlab R2012a), ground reaction force data were low-pass filtered (50Hz cutoff), and internal joint moments were computed using matched filter cutoffs (15Hz). EMG data were band pass filtered (15–300Hz cutoff), full-wave rectified, and low-pass fil
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br Experimental design materials and methods The data on the
2018-11-14

Experimental design, materials and methods The data on the tailored nanocomposite surface and fouling resistance properties are obtained using various analytical techniques. The wetting characteristics of the prepared nanocomposites were studied through mathematical view point using proper mathem
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br Acknowledgments This work was supported by National
2018-11-14

Acknowledgments This work was supported by National Natural Science Fund of China (Grant no. 61375079). Data The subsequent 52 files are for the specific environmental conditions, under which the six layer configurations are examined. The 52 files are the production of 13 climates and four oc
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Furthermore unlike Shahin et al who reported
2018-11-13

Furthermore, unlike Shahin et al., 2004, who reported an instrument specific enhancement of P2 component, we did not find any difference of P2 component between music and the two comparison groups. This may be related to the difference in musical training methods. While the music children in Shahin
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Introduction Neuroanatomical clinical and neuroimaging studi
2018-11-13

Introduction Neuroanatomical, clinical, and neuroimaging studies support the proposal that the cerebellum is involved in cognitive task performance. Much of the evidence linking cerebellar structure and function with cognitive performance is based on neuroimaging studies in adults (e.g., Hogan et a
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En algunos de estos pacientes el cambio de sexo
2018-11-13

En algunos de estos pacientes, el cambio de sexo no amenaza el sentido de su existencia, su núcleo identitario. Ellos pueden cambiar de sexo, cambiar su rol de género, pero no cambian su identidad de género. Stoller discute algunos supuestos de Money y sus colaboradores, por ejemplo, el trabajo que
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