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In this work we sought to commandeer
2018-11-09

In this work, we sought to commandeer an endogenous gene promoter to engineer custom-designed stem cells with the ability to regulate anti-cytokine therapy in an autonomous, real-time fashion. Critical to our selection of Ccl2 as the target locus for controlling transgene expression is the temporal
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br Experimental Procedures br Author
2018-11-09

Experimental Procedures Author Contributions P.D., D.O.F., V.F., and S.N. designed the study and reviewed the manuscript with input from S.G. and E.S., and all authors. P.D. contributed to every assay and analysis. B.S. and G.L. performed differentiation experiments, I.K. and C.T. Ca2+ imaging
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order SAR405 br Conclusion In this article
2018-11-09

Conclusion In this article we detailed the gist of the optogenetic method, its main components and application areas. This method is currently being rapidly developed and improved, and applied in an increasing number of scientific areas. Taking the optogenetic approach to studying various neurode
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Here are the amplitudes of
2018-11-09

Here are the amplitudes of g-harmonics of the crystal nuclear potential, which are determined by auda scattering amplitudes for crystal elementary cell (structural amplitudes). In general, are complex values, i.e. =expφ. However, if the crystal is nonabsorbing and centrosymmetric, all phases can be
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Then Eq can be rewritten in the following
2018-11-09

Then Eq. (3) can be rewritten in the following form, replacing the differentiation with respect to the dimensionless time by a variable dotted: Since the parameter T is arbitrary, let us set the following relationship between the newly-emerged multipliers: which separates the common multiplier o
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Table presents the odds ratios for health disparities
2018-11-09

Table 2 presents the odds-ratios for health disparities within the incarcerated and noninstitutionalized adult samples. The corresponding p-value denotes whether the health disparity (OR1 vs. OR2) differs significantly for incarcerated and noninstitutionalized adults. These findings are also present
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The characteristic technique of optimization involves varyin
2018-11-09

The characteristic technique of optimization involves varying one variable at a time and keeping the other constant. This method is not only laborious but does not also represent the complete effects of the variables in the process and ignores the combined interactions between the variables (Survase
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A limited number of studies have been conducted
2018-11-09

A limited number of studies have been conducted on the simultaneous oxidation of different casr of organochloride compounds and their relative performance with regards to photocatalyst adsorption selectivity. In this study, three structurally dissimilar organochloride compounds will be analysed for
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SVF and ASCs could be
2018-11-09

SVF and ASCs could be considered important enhancers of growth in our current model. Ex vivo expanded ASCs could potentially improve tissue growth in a way similar to that reported by Kølle et al. (Kølle et al., 2013). However, despite the reported advantages of using SVF/ASCs to enhance fat graftin
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purchase thapsigargin We did not find any difference in
2018-11-09

We did not find any difference in the percent of NBC infected with low or high MOI by IFA or RT-PCR. ZIKV could potentially use DC-SIGN and phosphatidylserine receptors, such as T-cell immunoglobulin and mucin domain (TIM) and TYRO3, AXL, and MER (TAM; Hamel et al., 2015; Meertens et al., 2012), or
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norepinephrine bitartrate br Funding Source This study was f
2018-11-09

Funding Source This study was funded by Mesoblast, Inc. Contributors Declaration of Interests Prior Presentation Acknowledgements Introduction In 1933, Henrik Sjögren, in his doctoral dissertation introduced the neologism, keratoconjunctivitis Sicca (Murube, 2010, Sjögren, 1933).
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Although some earlier studies reported significant differenc
2018-11-09

Although some earlier studies reported significant differences in RFS and PFS rates between risk groups (Xu et al., 2013; Altieri et al., 2012; Van Rhijn et al., 2010), other studies including ours (Fig. 1), found that prediction of both recurrence and progression were poorly discriminated by the EO
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Disclosure br Foxp regulatory T Treg cells are known to
2018-11-09

Disclosure Foxp3 regulatory T (Treg) strontium chloride are known to restrict anti-tumor immune responses and promote tumor progression (). Therapeutic utility of attenuating Treg cell function is one of the most exciting developments in the current field of tumor immunology. Temporary release f
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Alzheimer s disease is the most common progressive
2018-11-09

Alzheimer\'s disease is the most common progressive neurodegenerative dementia and is characterized by the accumulation of plaques and intra-neuronal fibrillary tangles, where the former consists of beta-amyloid peptides (Aβ) that are highly insoluble and toxic (Querfurth and LaFerla, 2010), and the
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As some of the material
2018-11-09

As some of the material in this review is speculative, it is worth being more concrete about specific lines of research to follow up on our suggestions. First, it would be important to establish whether there is indeed a developmental moderation of risk for SAD. More precisely, here, we make the sug
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