• Despite the clear evidence of

  2018-10-23

  

  Despite the clear evidence of these interventions, coverage is still low and therefore their impact to reduce mortality among newborns and children is very poor. The recent Lancet every newborn series (Bhutta et al., 2013, 2014) has clearly highlighted that approximately three-quarters of deaths und

• Cross talk between the various systems is

  2018-10-23

  

  Cross talk between the various systems is apparent with several well-described interactions such as that between C4-binding protein (C4BP) that regulates complement by inhibiting the classical initiation pathway and protein S, the latter being a cofactor for activated protein C, a regulator of coagu

• A multi biomarker based outcome stratification

  2018-10-23

  

  A multi-biomarker based outcome stratification model has also been advocated by Wong et al. that reliably estimated probability of mortality based on inflammatory markers along with conventional clinical and demographic data. Similar to our approach the sensitivity is much better than the specificit

• If confirmed in further research

  2018-10-23

  

  If confirmed in further research, our findings may provide an interesting new perspective on the non-specific effects of Stem Cell Compound Library and aid global efforts to reduce stunting and related negative health outcomes. Firstly, with regard to stunting, it seems that full and early coverage

• In addition to the cyclic

  2018-10-23

  

  In addition to the cyclic guanosine monophosphate-dependent protein kinase pathway, NO is known to regulate the function of target proteins through S-nitrosylation of cysteine residues (Hess et al., 2005; Jaffrey et al., 2001). One such target is the type 1 ryanodine receptor (RyR1), which is the Ca

• Our study pointed to a way for biomarker analysis or

  2018-10-23

  

  Our study pointed to a way for biomarker analysis or discovery and the possibility for cancer screening using the urine proteome. The algorithm for cancer screening illustrated a way to detect cancer with reduced false positive rate while keeping false negative rate in a reasonable range. Importantl

• As hypothesized pathogen presence in non

  2018-10-23

  

  As hypothesized, pathogen presence in non-diarrheal stool samples was associated with higher fecal MPO; this finding was also noted for AAT, although the AAT findings were evident only in younger children (aged 4˗11months). When fecal biomarkers were evaluated for associations with individual pathog

• br Materials and Methods br Results

  2018-10-23

  

  Materials and Methods Results Discussion Multidrug-resistant bacteria are a significant cause of sepsis, the most common cause of death in hospitalized patients, with an annual incidence of 1 million cases and 200,000 deaths in the U.S. alone (Deutschman and Tracey, 2014). This dire perspec

• br Materials and Methods br Results We characterized memory

  2018-10-23

  

  Materials and Methods Results We characterized memory B cell responses and HIV cross-neutralization potential in a cohort of ECs either positive or negative for the HLA-B*57 protective allele. We compared HLA-B*57+ and HLA-B*57− ECs with aviremic patients undergoing successful cART or HIV-nega

• Although low baseline virus load

  2018-10-23

  

  Although low baseline virus load is considered one of the predictive factors for SVR12, many other host, virus and drug related factors are also important and can sometimes affect the virus response to treatment regardless of baseline virus load. The significant existence of Resistance Associated Su

• br Immunolabeling Isolated mitochondria and

  2018-10-23

  

  Immunolabeling Isolated mitochondria and cardiomyocytes (neonatal and adult) were seeded in glass coverslips (0.17-mm thickness) coated with either poly-d-lysine or poly-l-lysine [0.1% (v/v) in PBS], respectively. After, 24h, samples were preloaded with 200nM mitotracker/ER tracker (as described

• br Protein molecular evolution analysis The protocol

  2018-10-23

  

  Protein molecular evolution analysis The protocol included new protein molecular evolution tests integrating patterns of nucleotide sequence similarities with protein tertiary structures. The MEGA program was used in calculations of codon usage statistics. Specifically, the ratios between observe

• br Data The data being shared describe the mechanical and

  2018-10-23

  

  Data The data being shared describe the mechanical and structural properties of healing rat myocardial infarcts from individual samples in several post-infarct time points: immediately (i.e. 0 day), 7, 14 and 28 days after the induction of myocardial infarction. The mechanical data are composed o

• Proteins from lysenin family were detected by

  2018-10-23

  

  Proteins from lysenin family were detected by Western blotting (WB) in coelomocyte-containing coelomic fluid of 9 adult earthworms, i.e. the 3 specimens (1–3) from the each group of earthworms, Ea, EfM−, EfM+, as described in [1]. The chemiluminescent signals were observed at the molecular weights 3

• More than half in number of the freshly

  2018-10-23

  

  More than half in number of the freshly-laid eggs (n=90) obtained from control (c355-GAL4/+) female flies after they have been crossed to males expressing dj-GFP (Fig. 1C and G) proved to be successfully fertilized, with GFP-tagged sperm being readily detected in their cytoplasm. Similarly, a 67% me

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